Table 1.

Important miRNAs in periodontal disease-related osteoclastogenesis.

miRNA	Function(s)	Target(s)	Reference(s)	Gingiva with Periodontitis	Reference(s)
miR-21	P	Pdcd4, FasL	[17,44]	UP	[8]
miR-29b	N	C-FOS, MMP-2	[22]	UP	[8]
miR-29a/b/c	P	Calcr, Cd93, Cdc42, Gpr85, Nfia, Srgap2	[23]	UP	[8]
miR-31	P	RhoA	[26]	DOWN	[10]
miR-34a	N	Tgif2	[27]	UP/DOWN	[8,11]
miR-124	N	NFATc1	[28,29]	Not reported
miR-125a	P/N	TRAF6, TNFIP3	[30,31]	UP	[8]
miR-141	N	Mitf, Calcr	[45]	DOWN	[10]
miR-146a	N	TRAF6	[32]	UP	[9]
miR-148a	P	MAFB	[46]	UP	[10]
miR-150	N	Opg	[47]	UP	[11]
miR-155	N	Mitf, Socs1, Pu.1	[1,38,48]	UP/DOWN	[9,10]
miR-223	P/N	NFI-A	[1,41,42,43]	UP	[10,11]

P, Positive regulator of osteoclastogenesis; N, Negative regulator of osteoclastogenesis.