Figure 4.
Effects of resveratrol (RSV) on neural apoptosis, brain edema, and neurological function at 24 h post subarachnoid hemorrhage (SAH). (A–D) RSV significantly reduced the elevated levels of cleaved caspase-3 and pro-apoptotic protein Bax, and enhanced the diminished level of Bcl2; (E,F) RSV administration markedly decreased the number of TUNEL-positive neural cells compared with the SAH + vehicle group; (G,H) RSV ameliorated brain edema and neurological behavior impairment at 24 h post SAH. Bars represent the mean ± SD. *** p < 0.001, ** p < 0.01, * p < 0.05, and ns means non-significant. Scale Bars = 50 μm.