Table 1.

IC₅₀ value of pseudoshikonin I on the activity of MMP-1, 2, 3, 9, and 13 in IL-1β-induced SW1353 cells ^a.

Matrix Metalloproteinase (MMP)	IC50 Value (μM)
MMP-1	58.7
MMP-2	60.8
MMP-3	>100
MMP-9	>100
MMP-13	63.3
TIMP-2	–

^a SW1353 cells incubated in the presence of 10, 25, 50, or 100 μM pseudoshikonin I stimulated with 20 ng/mL of IL-1β for 24 h. Results are expressed as the means ± S.D. of triple experiments.