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. 2016 Feb 3;310(9):R794–R805. doi: 10.1152/ajpregu.00366.2015

Fig. 5.

Fig. 5.

Overlapping distribution of TRPV3 agonist responses with TRPV1 in vagal afferent neurons from rat, WT mice, and TRPV3−/− mice. Eugenol, EVA, and FPP stimulate a subset of TRPV1 expressing (CAP sensitive) vagal afferent neurons. A: calcium trace showing the typical profile of a eugenol and CAP-sensitive rat vagal afferent neuron. B: percentage of neurons sensitive to eugenol (EUG) and CAP (rat: n = 37 neurons; WT mouse: n = 26 neurons; TRPV3−/− mice: n = 17 neurons). C: representative calcium trace of an EVA and CAP-sensitive rat vagal afferent neuron. D: percentage of neurons sensitive to EVA and CAP (rat: n = 60 neurons; WT mouse: n = 78 neurons; TRPV3−/− mice: n = 68 neurons). E: representative calcium trace showing a typical profile of a FPP and CAP-sensitive rat vagal afferent neuron. F: percentage of neurons sensitive to FPP and CAP (rats: n = 180 neurons; WT mouse: n = 170 neurons; TRPV3−/− mice: n = 100 neurons). G: FPP-EVA-Eugenol overlapping population of rat vagal afferent neurons. H: percentage of neurons sensitive to FPP, EVA, EUG (n = 150 neurons).