Table 2.
Longitudinal changes in retrobulbar blood flow velocity over four years in OAG patients of African and European descent.
| African Descent (AD) | European Descent (ED) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | 4-year | Change | Baseline | 4-year | Change | Comparison of change between races |
|||||||
| N | Mean (95% CI) |
N | Mean (95% CI) |
Mean (95% CI) |
p-value | N | Mean (95% CI) |
N | Mean (95% CI) |
Mean (95% CI) |
p-value | p-value | |
| OA PSV |
29 | 21.72 (18.64, 25.33) |
18 | 20.42 (17.14, 24.33) |
−1.39 (−5.25, 1.92) |
0.429 | 83 | 22.86 (20.44, 25.57) |
59 | 22.80 (20.27, 25.64) |
−0.06 (−2.11, 1.82) |
0.949 | 0.503 |
| OA EDV |
29 | 5.23 (4.51, 6.05) |
18 | 4.43 (3.60, 5.45) |
−0.95 (−2.12, 0.04) |
0.060 | 83 | 5.64 (5.04, 6.30) |
59 | 4.71 (4.12, 5.38) |
−1.11 (−1.79, −0.49) |
0.000 | 0.893 |
| OA RI |
29 | 0.760 (0.784, 0.733) |
18 | 0.789 (0.819, 0.754) |
0.033 (0.077, −0.005) |
0.090 | 83 | 0.752 (0.771, 0.731) |
59 | 0.792 (0.812, 0.771) |
0.048 (0.074, 0.025) |
0.000 | 0.567 |
| CRA PSV |
29 | 8.17 (7.29, 9.05) |
18 | 8.20 (7.10, 9.30) |
0.03 (−0.99, 1.04) |
0.958 | 83 | 7.88 (7.23, 8.54) |
60 | 7.75 (7.02, 8.47) |
−0.14 (−0.70, 0.43) |
0.629 | 0.777 |
| CRA EDV |
29 | 2.19 (1.92, 2.51) |
18 | 2.03 (1.74, 2.37) |
−0.18 (−0.62, 0.19) |
0.365 | 83 | 2.25 (2.04, 2.48) |
60 | 2.06 (1.86, 2.29) |
−0.21 (−0.45, 0.02) |
0.074 | 0.923 |
| CRA RI |
29 | 0.716 (0.689, 0.743) |
18 | 0.743 (0.714, 0.773) |
0.028 (−0.009, 0.064) |
0.141 | 83 | 0.698 (0.679, 0.718) |
60 | 0.724 (0.704, 0.744) |
0.025 (0.004, 0.047) |
0.018 | 0.925 |
| NPCA PSV |
29 | 7.50 (6.72, 8.28) |
18 | 8.16 (7.36, 8.95) |
0.65 (−0.15, 1.46) |
0.109 | 82 | 7.43 (6.86, 8.00) |
60 | 7.60 (7.05, 8.15) |
0.17 (−0.28, 0.62) |
0.4595 | 0.295 |
| NPCA EDV |
29 | 2.32 (2.06, 2.62) |
18 | 2.60 (2.26, 2.99) |
0.25 (−0.10, 0.55) |
0.156 | 82 | 2.38 (2.18, 2.60) |
60 | 2.27 (2.06, 2.49) |
−0.12 (−0.35, 0.09) |
0.278 | 0.076 |
| NPCA RI |
29 | 0.680 (0.653, 0.707) |
18 | 0.668 (0.637, 0.698) |
−0.013 (−0.050, 0.025) |
0.506 | 82 | 0.661 (0.641, 0.681) |
60 | 0.691 (0.670, 0.712) |
0.030 (0.009, 0.052) |
0.006 | 0.050 |
| TPCA PSV |
29 | 7.79 (7.02, 8.55) |
18 | 8.32 (7.42, 9.22) |
0.53 (−0.33, 1.40) |
0.224 | 83 | 7.59 (7.03, 8.15) |
60 | 7.82 (7.22, 8.42) |
0.23 (−0.25, 0.72) |
0.337 | 0.546 |
| TPCA EDV |
29 | 2.34 (2.08, 2.64) |
18 | 2.51 (2.20, 2.85) |
0.15 (−0.19, 0.45) |
0.362 | 83 | 2.35 (2.16, 2.56) |
60 | 2.27 (2.08, 2.48) |
−0.08 (−0.29, 0.11) |
0.416 | 0.230 |
| TPCA RI |
29 | 0.689 (0.716, 0.660) |
18 | 0.695 (0.722, 0.665) |
0.006 (0.045, −0.029) |
0.758 | 83 | 0.681 (0.701, 0.660) |
60 | 0.703 (0.722, 0.683) |
0.024 (0.047, 0.002) |
0.036 | 0.432 |
Bold P-values indicate statistical significance (p<0.05).
Note: OA blood flow assessment was unable to be obtained at four-year follow-up in one ED patient due to poor image quality.
Table 2 legend: CRA-central retinal artery; EDV–end diastolic velocity; NPCA–nasal posterior ciliary artery; OA-ophthalmic artery; OAG–open-angle glaucoma; PSV-peak systolic velocity; RI–resistive index; TPCA–temporal posterior ciliary artery.