Table 6.

Longitudinal changes in optic nerve head morphology from baseline to four-year follow-up in OAG patients of African and European descent.

		Race	Baseline Mean (n)	4-year Mean (n)	Mean change from baseline to follow-up	p-value	Comparison of change between races (p-value)
OCT	Cup area	AD	1.183 (29)	1.455 (19)	0.271	0.015	0.968
		ED	1.136 (83)	1.402 (64)	0.266	0.001
	Rim area	AD	1.188 (29)	0.998 (19)	−0.190	0.082	0.197
		ED	1.025 (83)	0.994 (64)	−0.031	0.600
	Cup/Disc area ratio	AD	0.494 (29)	0.590 (19)	0.096	0.028	0.335
		ED	0.528 (83)	0.576 (64)	0.049	0.042
	Cup/Disc horizontal ratio	AD	0.68 (29)	0.77 (19)	0.10	0.005	0.262
		ED	0.71 (83)	0.76 (64)	0.05	0.005
	Cup/Disc vertical ratio	AD	0.674 (29)	0.731 (19)	0.057	0.084	0.508
		ED	0.694 (83)	0.727 (64)	0.032	0.075
	RNFLT	AD	75.34 (29)	75.71 (20)	0.36	0.894	0.976
		ED	71.39 (83)	71.85 (64)	0.46	0.765
HRT-III	Cup area	AD	0.909 (29)	0.920 (20)	0.010	0.825	0.578
		ED	0.852 (82)	0.834 (66)	−0.017	0.479
	Rim area	AD	1.334 (29)	1.242 (20)	−0.092	0.089	0.047
		ED	1.191 (82)	1.219 (66)	0.028	0.345
	Rim volume	AD	0.320 (29)	0.299 (20)	−0.021	0.356	0.038
		ED	0.237 (82)	0.269 (66)	0.033	0.012
	Cup/Disc area ratio	AD	0.412 (29)	0.433 (20)	0.021	0.324	0.206
		ED	0.419 (82)	0.410 (66)	−0.009	0.447
	Linear cup/disc ratio	AD	0.625 (29)	0.638 (20)	0.013	0.437	0.390
		ED	0.624 (82)	0.621 (65)	−0.003	0.747
	RNFLT	AD	0.211 (29)	0.202 (20)	−0.009	0.506	0.162
		ED	0.163 (82)	0.176 (66)	0.013	0.102

Bold P-values indicate statistical significance (p<0.05).

Table 6 legend: AD-African descent; ED-European descent; n-number of participants; OAG-open angle glaucoma; HRT-III–Heidelberg retinal tomography-III; OCT–optical coherence tomography; RNFLT-retinal nerve fiber layer thickness.