TABLE 1.

Univariate and Multivariate Analysis of Preoperative Characteristics for Postoperative Survival in Patients with MSCC

Characteristics	Patients (n)	MOS (m)	Simple Cox Regression		Multiple Cox Regression
HR (95% CI)	P	HR (95% CI)	P
Age
≤56 yrs	106	8.8	1.21 (0.90–1.64)	0.21	Not included
>56 yrs	100	7.1
Gender
Female	101	8.4	1.30 (0.96–1.76)	0.09	Not included
Male	105	7.1
Primary site
Slow growth	40	18.3	1.78 (1.46–2.17)	<0.01	1.74 (1.41–2.15)	<0.01
Moderate growth	60	8.2
Rapid growth	106	5.3
Preoperative ambulatory status
Ambulatory	118	10.9	1.94 (1.43–2.64)	<0.01	2.04 (1.48–2.80)	<0.01
Not Ambulatory	88	5.6
ECOG performance status
1–2	105	10.9	1.66 (1.22–2.25)	<0.01	Not included
3–4	101	6.0
Number of involved vertebrae
1–2	110	8.4	1.21 (0.89–1.63)	0.22	Not included
≥3	96	6.4
Visceral metastases
No	107	11.7	2.21 (1.63–3.00)	<0.01	3.00 (2.17–4.13)	<0.01
Yes	99	4.5
Preoperative chemotherapy
No	117	5.8	2.14 (1.56–2.94)	<0.01	1.53 (1.08–2.16)	0.02
Yes	89	11.5
Bone metastasis at cancer diagnosis
No	99	10.8	1.77 (1.30–2.41)	<0.01	1.46 (1.05–2.02)	0.03
Yes	107	5.9
Time-developing motor deficits
≤14 d	105	6.2	1.64 (1.21–2.22)	<0.01	Not included
>14 d	101	10.8
Preoperative albumin
≤35 g/L	88	7.1	1.26 (0.93–1.71)	0.13	Not included
>35 g/L	118	7.7
Radical surgery at primary site
No	127	6.0	2.07 (1.50–2.86)	<0.01	Not included
Yes	79	11.7

CI indicates confidence interval; ECOG, Eastern Cooperative Oncology Group; HR, hazard ratio; m, months; MOS, median overall survival; MSCC, Metastatic spinal cord compression.