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. 2016 Aug 18;17(Suppl 4):543. doi: 10.1186/s12864-016-2792-1

Fig. 4.

Fig. 4

PARK2 influence zone. Detailed biological interpretation of PARK2 influence zone. a The PARK2 influence zone consists of 118 nodes and 119 edges. Red colored nodes correspond to upregulated genes, and green corresponds to downregulated genes. The epicenter is depicted using a hexagon. b GO enrichement of genes in PARK2 influence zone shows that most genes are involved in cell-cycle regulation. c Nodes downstream of PARK2 d Mechanistic insights into cell-cycle dysregulation upon PARK2 overexpression