Table 3.
Distribution of Streptomyces transporters in each TC class and subclass
| Class | Subclass | SACTE | SAV | SBI | SCAB | SCAT | SCO | SFLA | SGR | SHJG | STRVI | SVEN |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1: Channels/Proes | 22 | 31 | 29 | 34 | 22 | 29 | 26 | 28 | 26 | 31 | 30 | |
| 1.A: α-Type Channels | 18 | 24 | 20 | 25 | 15 | 22 | 21 | 20 | 21 | 24 | 21 | |
| 1.B: β-Barrel Porins | 3 | 6 | 7 | 8 | 6 | 6 | 4 | 5 | 4 | 6 | 6 | |
| 1.C: Pore-Forming Toxins (Proteins and Peptides) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | 1 | 1 | 3 | |
| 1.I: Membrane-bounded channels | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| 2: Electrochemical Potential-driven Transporters | 212 | 266 | 330 | 251 | 239 | 274 | 217 | 242 | 305 | 271 | 269 | |
| 2.A: Porters (uniporters, symporters, antiporters) | 212 | 266 | 328 | 251 | 239 | 274 | 217 | 242 | 305 | 271 | 269 | |
| 2.C: Ion-gradient-driven energizers | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| 3: Primary Active Transporters | 500 | 544 | 705 | 553 | 365 | 552 | 498 | 555 | 489 | 528 | 494 | |
| 3.A: P-P-bond-hydrolysis-driven transporters | 455 | 492 | 656 | 505 | 304 | 497 | 451 | 508 | 433 | 476 | 449 | |
| 3.B: Decarboxylation-driven transporters | 6 | 6 | 5 | 6 | 10 | 7 | 6 | 6 | 6 | 4 | 6 | |
| 3.D: Oxidoreduction-driven transporters | 39 | 46 | 43 | 42 | 51 | 48 | 41 | 41 | 50 | 47 | 39 | |
| 3.E: Light absorption-driven transporters | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |
| 4: Group Translocators | 27 | 46 | 62 | 54 | 35 | 30 | 36 | 40 | 46 | 37 | 43 | |
| 4.A: Phosphotransfer-driven group translocators | 5 | 7 | 4 | 5 | 2 | 8 | 8 | 6 | 5 | 7 | 6 | |
| 4.B: Nicotinamide ribonucleoside uptake transporters | 1 | 1 | 0 | 1 | 1 | 1 | 3 | 3 | 1 | 0 | 3 | |
| 4.C: Acyl CoA ligase-coupled transporters | 21 | 38 | 58 | 48 | 32 | 21 | 25 | 31 | 40 | 30 | 34 | |
| 5: Transmembrane Electron Carriers | 12 | 13 | 21 | 19 | 18 | 26 | 15 | 13 | 20 | 16 | 16 | |
| 5.A: Transmembrane 2-electron transfer carriers | 12 | 12 | 21 | 18 | 17 | 26 | 14 | 13 | 19 | 15 | 16 | |
| 5.B: Transmembrane 1-electron transfer carriers | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | |
| 8: Accessory Factors Involved in Transport | 4 | 4 | 5 | 6 | 5 | 5 | 5 | 6 | 6 | 4 | 4 | |
| 8.A: Auxiliary transport proteins | 4 | 4 | 5 | 6 | 5 | 5 | 5 | 6 | 6 | 4 | 4 | |
| 9: Incompletely Characterized Transport Systems | 60 | 63 | 74 | 67 | 75 | 67 | 68 | 66 | 63 | 69 | 55 | |
| 9.A: Recognized transporters of unknown biochemical mechanism | 27 | 25 | 44 | 27 | 33 | 31 | 32 | 35 | 27 | 33 | 25 | |
| 9.B: Putative transport proteins | 33 | 38 | 30 | 40 | 42 | 36 | 35 | 31 | 36 | 36 | 30 | |
| 9.C: Functionally characterized transporters lacking identified sequences | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | |
| N/A | 32 | 22 | 32 | 37 | 2 | 7 | 23 | 25 | 44 | 33 | 24 | |
| Total | 869 | 989 | 1258 | 1021 | 761 | 990 | 888 | 975 | 999 | 989 | 935 | |