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Knockdown of DNMT3a expression decreases the rate and intensity of calcium signaling in embryonic cardiomyocytes. A calcium assay kit was used to examine calcium transient peak signaling in the cardiomyocytes transfected with various siRNAs for 72 (A, B) and 96 h (C, D). (n = 4–8). *P < 0.05, ***P < 0.001 vs. negative siRNA.
