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MEA analysis of embryonic cardiomyocytes after knockdown of DNMT3a for 72 h
| Parameter | Negative siRNA | DNMT3a siRNA |
|---|---|---|
| Passed criteria/electrode [n (%)] | 57/60 (95) | 35/60 (58) |
| Beating rate (bpm) | 182.9 ± 34.3 | 125.0 ± 48.0 |
| Maximum peak amplitude (μV) | 268.8 ± 145.7 | 53.5 ± 32.6 |
| Minimum peak amplitude (μV) | −289.6 ± 174.5 | −106.5 ± 136.6 |
| Peak-peak amplitude (μV) | 558.4 ± 286.1 | 160.1 ± 133.3 |
| Interspike intervals (ms) | 336.2 ± 34.4 | 1263.3 ± 3255.9 |
