. 2016 Jun 17;30(9):3155–3170. doi: 10.1096/fj.201600257R

TABLE 3.

The TRPM8-dependence of gene expression in mouse germ cells subjected to mild or strong cold shocks

Markers	Gene	8°C	20°C	32°C
Germ cell markers	mMagea4	1.23	1.47	1.52
	mTnp1	1.21	1.31	1.53
	mPrm2	1.08	0.82	1.12
Cold/heat shock proteins	mHSF1	1.05	0.79	0.64^a
	mHSF2	0.94	0.97	1.00
	mCIRBP	0.96	1.20	0.89
	mHSPA1	1.14	1.23	1.28
	mHSPA2	0.89	0.72^a	0.66^a
Mitochondrial uncoupling	mUCP3	2.40^a	1.78^a	0.88
Oxidation	mSOD1	1.04	1.19	1.22
	mGPX2	1.72	2.23	0.83
	mGPX4	1.08	1.53^a	1.60^a
	mGPX5	6.90^b	5.35^b	0.73

Data are TRPM8-mediated fold-induction of gene expression. Values represent the ratio of averaged gene expression obtained by dividing CTL value by KOM8 value. Statistical analysis was achieved with 1-way ANOVA.

TRPM8-dependent repression.

TRPM8-dependent induction.