Table 1.
Baseline Characteristics for Patients with Symptomatic EBV and PTLD Disease
| All Patients | Symptomatic EBV | PTLD | ||||||
|---|---|---|---|---|---|---|---|---|
| N | % | N | % | P Value# | N | % | P Value# | |
| Total | 2283 | 100.0 | 199 | 100.0 | 75 | 100.0 | ||
| Gender | 1 | 0.0 | 0 | 0.0 | 0.23 | 0 | 0.0 | 0.41 |
| Missing | ||||||||
| Male | 1057 | 46.3 | 84 | 42.2 | 31 | 41.3 | ||
| Female | 1225 | 53.7 | 115 | 57.8 | 44 | 58.7 | ||
| EBV Status of Recipient and Donor | 54 | 2.4 | 2 | 1.0 | <.0001 | 1 | 1.3 | 0.0003 |
| R and D EBV unknown* | ||||||||
| R EBV +/ D EBV + | 209 | 9.2 | 8 | 4.0 | 5 | 6.7 | ||
| R EBV +/ D EBV − | 106 | 4.6 | 1 | 0.5 | 0 | 0.0 | ||
| R EBV +/ D EBV unknown* | 290 | 12.7 | 10 | 5.0 | 3 | 4.0 | ||
| R EBV −/ D EBV + | 484 | 21.2 | 42 | 21.1 | 13 | 17.3 | ||
| R EBV −/ D EBV − | 583 | 25.5 | 58 | 29.1 | 18 | 24.0 | ||
| R EBV −/ D EBV unknown* | 521 | 22.8 | 74 | 37.2 | 33 | 44.0 | ||
| R EBV unknown/ D EBV +* | 13 | 0.6 | 0 | 0.0 | 0 | 0.0 | ||
| R EBV unknown/ D EBV −* | 23 | 1.0 | 4 | 2.0 | 2 | 2.7 | ||
| Immunosuppression at Transplant | 94 | 4.1 | 6 | 3.0 | 0.85 | 2 | 2.7 | 0.65 |
| Missing | ||||||||
| CsA Base | 432 | 18.9 | 39 | 19.6 | 17 | 22.7 | ||
| Tac Base | 1596 | 69.9 | 138 | 69.3 | 52 | 69.3 | ||
| Other | 161 | 7.1 | 16 | 8.0 | 4 | 5.3 | ||
| Age at Transplant (mean ± SD) (year) | 2282 | 4.9 ± 5.3 | 199 | 2.7 ± 3.6 | <.0001 | 75 | 2.4 ± 3.2 | 0.0002 |
| Mo from transplant to SEBV/PTLD | -- | 199 | 11.2 ± 10.6 | -- | 75 | 12.7 ± 12.9 | -- | |
*
EBV unknown: Recipient / donor did not have EBV testing or data was missing.
#
Comparisons between SEBV and non SEBV or PTLD and non PTLD subjects