Table 1.
No. | AA | TOX | LUMO | nOHt | nHDon | logP | nNH2 | nCO | HLgap | IBEG |
---|---|---|---|---|---|---|---|---|---|---|
01 | 4.36 | 3.87 | 2.55 | 1 | 3 | 0.48 | 0 | 0 | 11.72 | 0 |
02 | 4.38 | 3.52 | 1.17 | 1 | 2 | 0.61 | 0 | 0 | 10.07 | 0 |
03 | 5.2 | 4.36 | −0.32 | 1 | 2 | 1.76 | 0 | 0 | 8.59 | 1 |
04 | 5.46 | 4.16 | −0.28 | 1 | 1 | 1.89 | 0 | 0 | 8.62 | 1 |
05 | 6.05 | 4.45 | −0.34 | 1 | 1 | 1.89 | 0 | 0 | 8.53 | 1 |
06 | 6.45 | - | −0.56 | 1 | 2 | −1.03 | 0 | 0 | 8.21 | 1 |
07 | 5.7 | 4.01 | −0.32 | 1 | 1 | 1.17 | 0 | 0 | 8.67 | 1 |
08 | 5.3 | 4.31 | −0.36 | 1 | 2 | 1.04 | 0 | 0 | 8.67 | 1 |
09 | 6.3 | 4.32 | −0.31 | 1 | 1 | 1.32 | 0 | 0 | 8.47 | 1 |
10 | 5.85 | 4.58 | −0.23 | 0 | 0 | 1.44 | 0 | 0 | 8.53 | 1 |
11 | 4 | 3.19 | 2.12 | 1 | 2 | −0.97 | 0 | 0 | 11.48 | 0 |
12 | 4.3 | 2.91 | 2.16 | 2 | 3 | −1.75 | 0 | 0 | 11.36 | 0 |
13 | 4.16 | 3.5 | 2.12 | 2 | 3 | −1.68 | 0 | 0 | 11.48 | 0 |
14 | 4.27 | 2.98 | 2.54 | 3 | 4 | −1.47 | 0 | 0 | 11.63 | 0 |
15 | 4.28 | 3.34 | 2.44 | 3 | 3 | −1.12 | 0 | 0 | 11.24 | 0 |
16 | 4.36 | 3.32 | 2.43 | 3 | 4 | −1.40 | 0 | 0 | 11.66 | 0 |
17 | 4.62 | 3.58 | 1.24 | 0 | 0 | −0.73 | 0 | 0 | 10.08 | 0 |
18 | 7.07 | 5.0 | −0.54 | 2 | 3 | −1.73 | 0 | 0 | 8.33 | 1 |
19 | 7.04 | 4.87 | −0.09 | 2 | 3 | −1.56 | 1 | 0 | 8.48 | 1 |
20 | 5.52 | 4.42 | −0.65 | 0 | 1 | −1.47 | 0 | 0 | 8.35 | 1 |
21 | 4.97 | 3.47 | −0.51 | 0 | 1 | −1.18 | 0 | 0 | 8.25 | 1 |
22 | 7.42 | 4.53 | −0.13 | 3 | 4 | −2.44 | 1 | 0 | 8.47 | 1 |
23 | 7.07 | 4.99 | −0.53 | 3 | 4 | −2.51 | 0 | 0 | 8.08 | 1 |
24 | 6.36 | - | −0.55 | 2 | 3 | −1.8 | 0 | 0 | 8.05 | 1 |
25 | 6.93 | 4.6 | −0.58 | 3 | 4 | −2.65 | 0 | 0 | 8.29 | 1 |
26 | 4.07 | 3.68 | 2.71 | 2 | 2 | −0.88 | 0 | 0 | 11.29 | 0 |
27 | 5.94 | 4.51 | −0.11 | 2 | 2 | 0.12 | 0 | 0 | 8.50 | 1 |
28 | 5.49 | 4.2 | −0.12 | 2 | 3 | −0.16 | 0 | 0 | 8.93 | 1 |
29 | 4.5 | 3.62 | 2.11 | 0 | 1 | −0.41 | 0 | 0 | 10.90 | 0 |
30 | 4.7 | 4.0 | 2.29 | 0 | 0 | 0.28 | 0 | 0 | 11.00 | 0 |
31 | 4.26 | 3.3 | 2.02 | 1 | 2 | −0.45 | 0 | 0 | 10.79 | 0 |
32 | 4.7 | 3.57 | 1.22 | 1 | 1 | −0.41 | 0 | 0 | 9.97 | 0 |
33 | 5.46 | 4.11 | −0.27 | 0 | 0 | 0.87 | 0 | 0 | 8.58 | 1 |
34 | 5.92 | 4.55 | −0.20 | 1 | 1 | 0.74 | 0 | 0 | 8.64 | 1 |
35 | 5.86 | 3.43 | −0.18 | 1 | 1 | 0.59 | 0 | 0 | 8.78 | 1 |
36 | 4.36 | 3.59 | 2.65 | 2 | 3 | −1.16 | 0 | 0 | 11.27 | 0 |
37 | 4.18 | 3.29 | 2.48 | 3 | 4 | −1.29 | 0 | 0 | 11.08 | 0 |
38 | 3.92 | 3.4 | 2.39 | 2 | 5 | −2.60 | 0 | 0 | 11.24 | 0 |
39 | 5.14 | 3.71 | −0.26 | 0 | 0 | −0.81 | 0 | 0 | 8.47 | 1 |
40 | 4.29 | 3.37 | 0.45 | 1 | 1 | 1.16 | 0 | 1 | 9.73 | 0 |
41 | 4.5 | 3.34 | 1.10 | 1 | 2 | 0.63 | 0 | 0 | 10.08 | 0 |
42 | 4.93 | 3.38 | 1.13 | 1 | 1 | 0.75 | 0 | 0 | 10.27 | 0 |
43 | 7.15 | 5.0 | −0.38 | 1 | 1 | 1.90 | 0 | 0 | 8.71 | 1 |
44 | 6.84 | 4.48 | −0.27 | 1 | 1 | 0.17 | 0 | 0 | 8.78 | 0 |
45 | 7.02 | 4.94 | −0.38 | 1 | 1 | 0.91 | 0 | 0 | 8.71 | 1 |
46 | 5.44 | 4.12 | −0.39 | 1 | 1 | −0.08 | 0 | 0 | 8.68 | 1 |
47 | 5.45 | 3.93 | 0.04 | 1 | 1 | 1.84 | 0 | 0 | 9.08 | 1 |
48 | 6.44 | 4.3 | −1.25 | 1 | 1 | 1.02 | 0 | 0 | 7.98 | 1 |
49 | 4.7 | 3.4 | 0.64 | 0 | 2 | 1.99 | 0 | 1 | 9.77 | 0 |
50 | 4.47 | 3.47 | 0.98 | 0 | 2 | 2.31 | 0 | 1 | 10.04 | 0 |
51 | 4.56 | 3.61 | 0.89 | 0 | 3 | 1.62 | 0 | 0 | 9.87 | 0 |
52 | 4.65 | 3.64 | 0.85 | 0 | 3 | 1.62 | 0 | 0 | 9.89 | 0 |
53 | 4.63 | 3.47 | 0.58 | 0 | 1 | 2.43 | 0 | 1 | 9.82 | 0 |
54 | 4.42 | 3.42 | 0.50 | 0 | 1 | 2.12 | 0 | 1 | 9.24 | 0 |
55 | 4.39 | 3.53 | 0.42 | 0 | 0 | 2.25 | 0 | 1 | 9.27 | 0 |
56 | 4.42 | 3.6 | 0.64 | 0 | 2 | 1.75 | 0 | 0 | 9.70 | 0 |
57 | 4.42 | 3.6 | 0.74 | 0 | 2 | 1.75 | 0 | 0 | 9.34 | 0 |
58 | 4.23 | 3.63 | 0.68 | 0 | 2 | 2.78 | 0 | 0 | 9.28 | 0 |
59 | 4.34 | 3.83 | 0.74 | 0 | 2 | 3.17 | 0 | 0 | 9.34 | 0 |
60 | 6.28 | 4.19 | 0.01 | 0 | 2 | 2.90 | 0 | 0 | 8.59 | 1 |
61 | 5.75 | 4.05 | −0.20 | 0 | 1 | 3.27 | 0 | 1 | 8.53 | 1 |
62 | 4.53 | 3.58 | −0.56 | 0 | 0 | 5.46 | 0 | 0 | 8.09 | 1 |
63 | 4.36 | 3.35 | 2.83 | 1 | 3 | 1.52 | 0 | 0 | 11.539 | 0 |
64 | 4.36 | 3.93 | 2.22 | 1 | 1 | 2.90 | 0 | 0 | 10.87 | 0 |
65 | 4.37 | 3.35 | 0.72 | 0 | 0 | 2.51 | 0 | 1 | 9.30 | 0 |