Table 2. Nomenclature of the regulatory proteins involved in the cohesion cycle.
| Mammals | D. melanogaster | S. cerevisiae | S. pombe | Function |
|---|---|---|---|---|
| NIPBL/SCC2 | Nipped-B | Scc2 | Mis4 | Cohesin loading |
| MAU2/SCC4 | Mau2 | Scc4 | Ssl3 | Cohesin loading |
| ESCO1 | Eco/Deco | Eco1/Ctf7 | Eso1 | Cohesion establishment |
| ESCO2 | San | |||
| PDS5A | Pds5 | Pds5 | Pds5 | Cohesion maintenance |
| PDS5B/APRIN | ||||
| WAPL/WAPAL | Wapl | Rad61/Wpl1 | Wpl1 | Cohesion maintenance |
| SORONIN/CDCA5 | Dmt (Dalmatian) | – | – | Cohesion maintenance |
| HDAC8 | – | Hos1 | – | Cohesin deacetylase |
| Shugosin1 | Sse1 | Esp1 | Protection of centromeric cohesion | |
| Separase | Sse1 | Esp1 | Separase | Cohesin removal |
| Polo like Kinase 1 (PLK1) | Polo | Cdc5 | Plk1 | Cohesin removal |