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. 2016 Jul 12;44(14):6583–6598. doi: 10.1093/nar/gkw638

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© The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 4. — Time course of PTC readthrough. HDQ-P1 were exposed to compounds for different times and analysed for formation of full-length p53 (A and B), and TP53 mRNA (C). Panel A shows representative time points for G418 and CDX5-1 and the entire time course for the combination of G418 and CDX5-1. Panel B shows quantitation of full-length p53 relative to the amount of truncated p53 found in untreated cells for the entire time course for all three treatments. Panel C shows triplicate measurements of TP53 mRNA (± S.D., n = 3) from the same samples as panels A and B. * indicates statistically significant differences between different treatment conditions and untreated samples (P < 0.05).