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. Author manuscript; available in PMC: 2017 Jul 18.
Published in final edited form as: Angew Chem Int Ed Engl. 2016 May 31;55(30):8639–8642. doi: 10.1002/anie.201603420

Figure 3.

Figure 3

Biological activities of Ts3 protein candidates. a) Disruption of rNav1.4 fast inactivation compared among the 4 different candidate Ts3 proteins. Na+ ionic current, elicited by a step-pulse to −10 mV from a holding potential of −90 mV, was measured without (blue traces) and with (red traces) 210 nM of each candidate protein. b) Dose-response assay of rNav1.4 fast inactivation modification by Ts3(1-64)-CONH2 protein. The right panel shows the proportion of the slower component of the fit as a function of toxin concentration. Error bars indicate standard error of the mean (number of cells = 3-6 cells).