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. Author manuscript; available in PMC: 2017 Jul 18.
Published in final edited form as: Angew Chem Int Ed Engl. 2016 May 31;55(30):8639–8642. doi: 10.1002/anie.201603420

Figure 4.

Figure 4

Figure 4

Figure 4

Figure 4

Figure 4

Crystal structure of Ts3(1-64)-CONH2 toxin protein. a) Crystal structre of the D/L racemate of Ts3(1-64)-CONH2 protein, (PDB 5CY0). Cartoon representation of the packing of d-Ts3(1-64)-CONH2 (Cyan) and l-Ts3(1-64)-CONH2 (Green) proteins in the unit cell in P1<bar>. b) Structure alignment of Ts3 toxin (green) and alpha scorpion toxin LQH-α-IT (golden) and Aah2 (magenta).[20] c) Core domain hydrophobic surface comparison between Ts3 and other alpha scorpion toxins. d) NC-domain comparison between Ts3 and other alpha scorpion toxins. e) Hydrogen bonding of Asn11 and Lys57 with residues in the C-terminal region of Ts3.