Table 1.
Subtypes of vasopressin receptors, location, and function
Receptor | Location | Function |
---|---|---|
V1A | Vascular smooth muscle, platelet, hepatocyte, myometrium | Vasoconstriction, platelet aggregation, myocardial hypertrophy |
V1B | Anterior pituitary | Release of ACTH, prolactin, and endorphins |
V2 | Collecting duct of kidney, vascular endothelium, and vascular smooth muscle cell | Insertion of AQP2 channels into apical membrane of collecting duct, release of von Willebrand factor, and factor VIII |
Abbreviation: ACTH, adrenocorticotropic hormone.