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. 2016 Aug 22;9:5181–5193. doi: 10.2147/OTT.S105198

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© 2016 Xiao et al. This work is published and licensed by Dove Medical Press Limited

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MiR-126 inhibits the expression of PIK3R2 and PI3K/Akt signaling pathways.

Notes: (A) Expression of PIK3R2 mRNA detected by qRT-PCR in histogram; (B) the expression of PIK3R2 protein detected by Western blot; and (C) the protein expressions of PI3K, p-PI3K, p-Akt, and Akt in PI3K/Akt signaling pathway detected by Western blot. *P<0.05; ***P<0.001.

Abbreviations: Akt, protein kinase B; p-Akt, phosphorylated-Akt; PI3K, phosphatidylinositol 3 kinase; p-PI3K, phosphorylated-PI3K; PIK3R2, phosphatidylinositol 3-kinase regulatory subunit beta; qRT-PCR, quantitative real-time polymerase chain reaction.