Table 1.

Examples of SVBs and DisGeNET query terms used to extract SVB-related diseases and genes potentially involved in perturbation of SVBs

SVB	SVB query term used	Example Disease Names	Example Genes Implicated
Vitamin D	“Vitamin_D”	Vitamin D Deficiency, Rickets Hereditary Vitamin D-Resistant	DHCR7, VDR
Parathyroid hormone	“Parathyroid”	Pseudo-hypoparathyroidism, Parathyroid Neoplasms	GNAS, CDC73
Vitamin C	“ascorbic acid”	Ascorbic Acid Deficiency	GSTK1, HP, SLCO6A1
Vitamin K	“Vitamin_K”	Vitamin K Deficiency, Vitamin K Dependent Clotting Factors Combined Deficiency	GGCX, VKORC1, F7
Neutrophil	“Neutrophil”	Neutrophil Actin Dysfunction, Hereditary Neutrophilia	PARP1, CYBA, CSF3R
Eosinophil	“Eosinophil”	Eosinophilia, Hyper-eosinophilic Syndrome	IL5, FIP1L1, PDGFRA
Hemoglobin	“Hemoglobin”	Hemoglobinopathies, Methemoglobinemia	HBB, CYP1A2, HBA1
Estrogen	“Estrogen”	Oestrogen deficiency, Estrogen Resistance	ESR1, RBBP4, BCAR1, PPP2CA