Table 3.
Serum levels of oxidant/antioxidant status before and after radiotherapy in different BMI groups.
Variables | BMI ≤30 kg/m2 (n = 42) | BMI >30 kg/m2 (n = 38) | p value | |
---|---|---|---|---|
TAS (μmol/L) | Before RT | 546.0 ± 190.6 | 512.7 ± 189.2 | 0.472 |
After RT | 261.9 ± 62.4 | 275.3 ± 54.0 | 0.500 | |
p value | <0.001 | <0.001 | ||
MDA (μmol/L) | Before RT | 2.0 ± 0.5 | 1.9 ± 0.5 | 0.999 |
After RT | 2.3 ± 1.1 | 2.2 ± 1.1 | 0.881 | |
p value | 0.152 | 0.106 | ||
SOD (pg/ml) | Before RT | 201.3 ± 288.0 | 293.1 ± 516.2 | 0.165 |
After RT | 99.5 ± 45.7 | 103.8 ± 56.0 | 0.165 | |
p value | 0.017 | 0.024 | ||
CAT (pg/ml) | Before RT | 651.5 ± 548.7 | 543.6 ± 562.6 | 0.713 |
After RT | 657.5 ± 941.1 | 657.8 ± 494.2 | 0.892 | |
p value | 0.950 | 0.406 | ||
GPx (μIU/ml) | Before RT | 106.1 ± 103.9 | 131.5 ± 22.2 | 0.456 |
After RT | 73.6 ± 43.2 | 83.8 ± 83.0 | 0.135 | |
p value | 0.046 | 0.009 | ||
Se (μg/L) | Before RT | 51.4 ± 25.5 | 52.2 ± 34.5 | 0.284 |
After RT | 43.5 ± 21.8 | 39.0 ± 16.8 | 0.557 | |
p value | 0.144 | 0.053 |
Notes: BMI: Body mass index (kg/m2); TAS: total antioxidant status; MDA: malondialdehyde; SOD: superoxide dismutase; CAT: catalase; GPx: glutathione peroxidase; Se: selenium; RT: radiotherapy; data expressed as mean ± SD; p < 0.05.