Table 2.
Average Number of Lipid-Water Hydrogen Bonds per Lipid Molecule in Each of the Bilayers Studied
| DSPC |
ISIS | HDHD | ||||
|---|---|---|---|---|---|---|
| Total | Phos. | Glyc. | Tails | |||
| DPPC | 3.42 (0.12) | 0.652 | 0.022 | 0.326 | ||
| DSPC | 3.29 (0.09) | 0.632 | 0.034 | 0.334 | ||
| ISIS | 0.75 (0.06) | |||||
| HDHD | 0.71 (0.06) | |||||
| DSPC-ISIS | 3.90 (0.14) | 0.599 | 0.041 | 0.361 | 0.61 (0.06) | |
| DSPC-HDHD | 3.96 (0.22) | 0.619 | 0.031 | 0.350 | 0.55 (0.08) | |
| ISIS-HDHD | 0.68 (0.09) | 0.80 (0.09) | ||||
| DSPC-ISIS-HDHD | 4.28 (0.24) | 0.605 | 0.036 | 0.359 | 0.59 (0.10) | 0.58 (0.10) |
The average numbers of hydrogen bonds per DPPC and DSPC molecule are decomposed into fractions associated with different parts of the molecule, as shown in Fig. 4. In the ISIS and HDHD molecules, only the headgroups are involved in hydrogen bonds. The numbers in parentheses are error estimates based on the standard deviation.