Figure 4.

Differences in the average energies of the components contributing to $\Delta H^{\text{sol}}\approx \Delta U^{\text{sol}}$ for flexible Gly₂ (left) and Gly₅ (right). The subscript u denotes the solute/peptide and v denotes the solvent. $\Delta U^b$ is the difference between the average bonded intrapeptide energies (e.g., dihedral, bond, angle energies) of oligoglycine in the final, solvated state and the gas phase.