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(A) The NMR structure of human PrP (90–231) ((39) PDB: 2LSB) generated using PyMOL (Version 1.8, Schrödinger, LLC, New York). The single (intrinsic) Trp located at the 99th position of the N-terminal unstructured region is shown in yellow. (B) Time-resolved fluorescence anisotropy decay of PrP. The inset shows the global fitting of I||(t) and I⊥(t). To see this figure in color, go online.
