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. 2016 Aug 26;16(1):103. doi: 10.1186/s12876-016-0520-6

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Study selection and flow-chart of UC patients’ 1-year follow-up. a Follow-up scheme protocol performed in active UC patients receiving conventional therapy (baseline). Responder UC patients completed the entire follow-up period. Non-responder patients re-started the follow-up with biological therapy and were examined at 1 month, 14 weeks, 6 and 12 months. Clinical subscore, FC and serum sST2 were evaluated at 1, 3, 6 and 12 months. Endoscopic subscore and intestinal ST2 were determined at baseline, 14 weeks (w) and 6 months. b Flow-chart of patients enrolled in the follow-up