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. 2016 Aug 26;13(1):204. doi: 10.1186/s12974-016-0661-0

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Exendin-4 treatment preserved BBB integrity in warfarin-associated HT after cerebral ischemia. Western blot analysis of a, b p-GSK-3β/GSK-3β; c, d p-β-catenin/β-catenin; e, f claudin-3; and g, h claudin-5. Representative blots from six independent experiments with similar results are shown. (Sham: sham-operated group, Ctrl: MCAO group, W: warfarin-associated HT group, W + Ex-4: warfarin-associated HT pretreatment with Ex-4). Data are presented as mean ± SD from six independent experiments and analyzed by one-way ANOVA. *P < 0.05 vs. MCAO group; ^# P < 0.05 compared with warfarin-associated HT group