Table 5.
Association between plasma IL-6 concentration and metabolic syndrome, and the mediation effect of MS components
| OR (95 % CI) | OR (95 % CI) | OR (95 % CI) | OR (95 % CI) | OR (95 % CI) | OR (95 % CI) | ||
|---|---|---|---|---|---|---|---|
| MetS-IDF | Age (years) | 1.072 (1.040- 1.105) | 1.072 (1.038-1.108) | 1.076 (1.042- 1.111) | 1.072 (1.037- 1.109) | 1.091 (1.053- 1.129) | 1.068 (1.032- 1.105) |
| Sex (men) | 0.357 (0.205- 0.624) | 0.405 (0.223-0.738) | 0.345 (0.190- 0.626) | 0.957 (0.481- 1.907) | 0.690 (0.364- 1.309) | 0.493 (0.262- 0.927) | |
| IL-6 (pg/ml) | 1.086 (0.975- 1.210) | 1.051 (0.935-1.182) | 1.054 (0.934- 1.191) | 1.021 (0.894- 1.166) | 0.968 (0.853- 1.099) | 1.033 (0.907- 1.176) | |
| Insulin (mU/L) | - | 1.154 (1.090-1.221) | - | - | - | - | |
| BMI (kg/m2) | - | - | 1.139 (1.073- 1.209) | - | - | - | |
| Waist circumference (cm) | - | - | - | 1.097 (1.065- 1.131) | - | - | |
| HDL-cholesterol (mmol/L) | - | - | - | - | 0.893 (0.861- 0.925) | - | |
| Triglycerides (mmol/L) | - | - | - | - | - | 1.023 (1.015- 1.030) | |
| MetS-AHA/NHLBI | Age (years) | 1.066 (1.034- 1.098) | 1.067 (1.033-1.103) | 1.072 (1.038- 1.108) | 1.068 (1.031- 1.105) | 1.090 (1.051- 1.131) | 1.063 (1.026- 1.102) |
| Sex (men) | 0.395 (0.224- 0.695) | 0.456 (0.246-0.844) | 0.372 (0.201- 0.689) | 1.171 (0.573- 2.395) | 0.923 (0.467- 1.824) | 0.579 (0.299- 1.123) | |
| IL-6 (pg/ml) | 1.064 (0.954- 1.186) | 1.024 (0.907-1.156) | 1.019 (0.894- 1.162) | 0.983 (0.854- 1.131) | 0.918 (0.805- 1.048) | 0.995 (0.870- 1.139) | |
| Insulin (mU/L) | - | 1.168 (1.103-1.237) | - | - | - | - | |
| BMI (kg/m2) | - | - | 1.167 (1.094- 1.244) | - | - | - | |
| Waist circumference (cm) | - | - | - | 1.110 (1.075- 1.146) | - | - | |
| HDL-cholesterol (mmol/L) | - | - | - | - | 0.865 (0.830- 0.902) | - | |
| Triglycerides (mmol/L) | - | - | - | - | - | 1.026 (1.018- 1.034) |