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. 2016 Aug 27;13(1):208. doi: 10.1186/s12974-016-0685-5

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — miR-17-92 cluster regulates astrocytogenesis and neurogenesis of grafted NSCs. a, c Expression of GFAP (red) or NeuN (red) in transplanted CON-NSC or miR-17-92-NSC cells (green), 12 weeks after injury and transplantation. Arrows in c indicate double positive cells. Scale bar, 100 μm. The framed areas in c are shown at higher magnification. Scale bar, 10 μm. b, d Percentage of GFAP-positive or NeuN-positive cells among total EGFP-positive cells from the experiment shown in a or c was determined. Values are means ± SEM. Asterisks indicate a statistically significant difference compared with the control group (*P < 0.05, unpaired two-tailed t test, n = 3 independent experiments)