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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Hum Genet. 2016 May 12;135(9):1059–1070. doi: 10.1007/s00439-016-1678-2

Fig. 1. TALEN pair targeting HIV proviral DNA.

Fig. 1

Example of TALEN binding, cleavage and repair of double strand breaks. TALENs bind and cleave a DNA target sequence; the HIV LTR sequence is the example shown (Strong et al. 2015). Endogenous NHEJ repair of double strand breaks introduces indels.