Table 1.

Numbers of fixed preferred, unpreferred substitutions and number of preferred, unpreferred sites.

Gene	P sites	P fixations	U sites	U fixations	aRP/U	bFET p-value
CG9723	52	11	245	6	8.638	0.000044*
CG10920	38	9	261	10	6.182	0.000472*
CG7387	48	7	237	4	8.641	0.000971*
CG13189	29	6	201	5	8.317	0.00168*
CG15717	24	5	148	3	10.278	0.0031*
CG7840	37	6	177	4	7.176	0.00416*
CG10035	39	6	150	3	7.692	0.00497*
CG3024	36	7	180	7	5.000	0.00616*
CG1749	63	8	142	3	6.011	0.00665*
CG6459	30	6	138	5	5.520	0.00957*
CG12276	51	6	144	3	5.647	0.0155*
CG3085	44	4	218	3	6.606	0.0209*
CG9135	65	7.5	230	7.5	3.538	0.0283
CG6981	13	3	101	3	7.769	0.0307
CG6971	36	5	110	4	3.819	0.0555
CG2577	22	3	229	12	2.602	0.156
CG5499	15	1	56	0	N.A	0.222
CG2222	19	2	125	5	2.632	0.251
CG9383	25	5	100	11	1.818	0.333
CG10252	31	3	99	5	1.916	0.407
CG6036	57	7	136	10	1.670	0.409
CG5272	37	1	108	8	0.365	0.454
CG8277	37	0	112	4	0	0.573
CG15336	17	2	56	4	1.647	0.627
CG1239	60	4	104	10	0.693	0.773
CG3509	51	4	120	12	0.784	0.782
CG10853	29	1	69	1	2.379	1
CG11981	23	1	112	6	0.812	1
CG18418	30	1	179	7	0.852	1
CG5915	27	0	102	2	0	1
CG4593	19	1	117	6	1.026	1
CG11379	16	1	145	8.5	1.066	1
Total	1120	134	4651	182	3.057	7.07E-18*

^aRatio of fixed preferred variants per preferred sites over fixed unpreferred variants per unpreferred sites.

^bSignificance was determined after the two-tailed Fisher’s Exact Test (FET) and shown are the resulting p-values.

^*Significant p-value < 0.05 after correcting for multiple hypothesis testing using the method of Benjamini-Hochberg (1995).

N.A, not appilicable.