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. Author manuscript; available in PMC: 2016 Aug 28.
Published in final edited form as: Curr Alzheimer Res. 2012 Jul;9(6):746–758. doi: 10.2174/156720512801322564

Fig. (3).

Fig. (3)

Schematic structure of eight NR1 receptor isoforms (NR1A–H). Exons 5, 21 and 22 encode three splice cassettes named N1, C1 and C2. Carboxy-terminals variants are generated by splicing out of cassettes C1 and/or C2; and amino-terminal variant, by splicing out of N1. If C2 is excised, the first stop codon is suppressed, resulting in a new open reading frame that encodes the sequence named C2’ [143].