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. Author manuscript; available in PMC: 2016 Aug 28.
Published in final edited form as: Curr Top Dev Biol. 2016 Apr 25;119:27–61. doi: 10.1016/bs.ctdb.2016.03.004

Figure 1. Developmental and biochemical control of pigmentation in Drosophila.

Figure 1

A simplified version of the biochemical pathway controlling pigment biosynthesis in insects is shown with regulators controlling expression of individual pigment synthesis genes in at least one Drosophila species overlaid. Genes colored red are part of the pigment biosynthesis pathway; metabolites are colored gray; and gray arrows indicate chemical reactions during pigmentation synthesis. Genes colored in blue are part of the regulatory network that directly (solid arrows) or indirectly (broken arrows) modulate enzyme expression during pigmentation development in Drosophila. Pointed and blunt arrows indicate positive and negative regulatory interactions, respectively. The pigment biosynthesis pathway is conserved among all Drosophila, but the regulatory relationships shown often function in only a subset of Drosophila species (Gompel et al. 2005; Arnoult et al. 2013).