A. After recording basal sIPSCs, the external solution was changed to eACSF for 20 min. Traces show the effects of eACSF on sIPSCs in a MSN from a 70 day-old R6/2 mouse. B. The average frequency of events was reduced (Student’s t-test, t=2.19, p=0.049). C. The cumulative amplitude distribution showed a small, non-significant leftward shift after eACSF, indicating only a trend for reduced number of large-amplitude events. D. The cumulative IEI probability distribution showed a rightward shift, indicating reductions in frequency after eACSF [two-way RM ANOVA, F(150,150)=3.669, p<0.001].