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. 2016 Aug 29;7:350. doi: 10.3389/fphys.2016.00350

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Copyright © 2016 Zuo, He, Tinsley, Pannell, Ward and Arciero.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic illustrating the experiment timeline comprised of a 12-week WL (phase 1), followed by a 52-week WL-M (phase 2). HP-IF-LC, high-protein, intermittent fasting, low-calorie; HH diet, heart healthy diet; WL, weight loss; WL-M, weight loss maintenance.