Table 1.

Somatic mutations identified by tumor whole-exome sequencing

Gene	Genomic coordinates (hg19)	HGVS cDNA	HGVS protein	Variant type	COSMIC ID	Variant allele fraction
FGFR1	Chr 8: 38274849	NM_023110: c.1638C>A	p.N546K	Missense	COSM19176	0.29
PIK3CA	Chr 3: 178952085	NM_006218: c.3140A>G	p.H1047R	Missense	COSM775	0.33
PPP1R1A	Chr 12: 54975791	NM_006741: c.372_373 delinsCA	p.E124_S125 delinsDT	Dinucleotide substitution	N/A	0.38
RNF216	Chr 7: 5662795	NM_207116: c.2297G>A	p.R766H	Missense	N/A	0.21

HGVS, Human Genome Variation Society; COSMIC, Catalogue of Somatic Mutations in Cancer; N/A, not applicable.