Table 2.

Proportion of patients with minimum clinically important change (MCIC)^a in EPIC quality-of-life scores by treatment group.

	Average change			Worst change
Summary domain	Study 1 (35 Gy/5 F)	Study 2 (40 Gy/5 F)	p-Value	Study 1 (35 Gy/5 F)	Study 2 (40 Gy/5 F)	p-Value
Urinary			0.60			0.50
No MCIC	66 (80.5%)	22 (75.9%)		27 (32.9%)	12 (41.4%)
MCIC	16 (19.5%)	7 (24.1%)		55 (67.1%)	17 (58.6%)
Bowel			0.16			0.82
No MCIC	60 (73.2%)	17 (58.6%)		28 (34.2%)	11 (37.9%)
MCIC	22 (26.8%)	12 (41.4%)		54 (65.9%)	18 (62.1%)
Sexual			0.82			0.24
No MCIC	44 (57.1%)	16 (61.5%)		27 (35.1%)	13 (50.0%)
MCIC	33 (42.9%)	10 (38.5%)		50 (64.9%)	13 (50.0%)

QOL, quality of life; EPIC, Expanded prostate cancer index composite.

^aMinimum clinically important change defined as a decrease in quality of life from baseline to follow-up which exceeds half of the standard deviation of the baseline value (10).