Table II. Clinical Variables in Patients With and Without Backwash Ileitis.
| Backwash-Positive (n=39) | Backwash-Negative (n=295) | p value | |
|---|---|---|---|
| Sex (M/F) | 20/19 | 166/129 | 0.61 |
| Median age (range) | 36 (8-67) | 38 (9-81) | 0.32 |
| Median disease duration (mo) | 61 | 60 | 0.58 |
| Disease Extent | |||
| Pancolitis | 39 (100) | 219 (74) | 0.0001 |
| Left-sided | 0 (0) | 73 (25) | |
| Proctitis | 0 (0) | 3 (1) | |
| Preoperative medication | |||
| Steroids | 4 (10) | 42 (14) | 0.80 |
| Immunomodulators | 28 (72) | 209 (71) | |
| Extraintestinal disease | 13 (33) | 62 (21) | 0.10 |
| Arthritis | 5 (13) | 21 (7) | 0.20 |
| PSC | 6 (15) | 6 (2) | 0.001* |
| Other | 2 (5) | 35 (12) | 0.28 |
| Family history of IBD | 8 (21) | 82 (28) | 0.44 |
| Ulcerative colitis | 4 (10) | 59 (20) | |
| Crohn's disease | 5 (13) | 29 (10) | |
| Perianal disease | 5 (13) | 12 (4) | 0.04 |
| Preoperative type of colitis | |||
| Ulcerative colitis | 19 (49) | 218 (74) | 0.002 |
| IBDU | 20 (51) | 77 (26) | |
| Postoperative type of colitis | |||
| Ulcerative colitis | 16 (41) | 220 (75) | 0.0001 |
| IC | 23 (59) | 75 (25) | |
| Indication for IPAA | |||
| Medically unresponsive | 32 (82) | 249 (84) | 0.65 |
| Cancer / dysplasia | 7 (18) | 46 (16) | |
*
comparison of PSC between BWI+ and BWI-negative patient groups
PSC primary sclerosing cholangitis
IBD inflammatory bowel disease
IBDU inflammatory bowel disease unclassified
IC indeterminate colitis
IPAA ileal pouch-anal anastomosis