TABLE I.
CVD-Related Microarray Datasets and Data-Derived Optimal Prediction Models
| Dataset 1 | Dataset 2 | Dataset 3 | Dataset 4 | |
|---|---|---|---|---|
| Description | Blood Gene Exp. CAD | Baseline Macro. Athero. | Monocytes Fam. Hyper. | Monocytes Athero. |
|
| ||||
| GEO Accession | GSE12288 [123] | GSE9874 [2] | GSE6054 [124] | GSE23746 |
|
| ||||
| # of Samples | 222 | 30 | 23 | 95 |
|
| ||||
| Array Platform | Affy. HG U133A | Affy. HG U133A | Affy. HG U133 Plus 2.0 | Illumina Beadchip |
|
| ||||
| Classifier | KNN, K=10 | Linear SVM, Cost=4 | Linear SVM, Cost=1 | Bayesian, Near. Cent. |
|
| ||||
| Feature Selection Method | mRMRQ | T-Test | Fold Change | T-Test |
|
| ||||
| # of Features | 20 | 5 | 1 | 2 |
|
| ||||
| Est. Accuracy | 0.61 ±0.05 | 0.87 ±0.05 | 0.55 ±0.06 | 0.97 ±0.04 |