RSFC of the MPFC in young vs. older adults using GRS+Scrubbing (A-C) and ANATICOR (D-F). A and D) In young adults, the MPFC shows positive RSFC with other regions of the default network (warm colors), and negative RSFC with only dorsal attention network regions (cool colors). B and E) In older adults, the MPFC shows reduced RSFC with other regions of the default network (warm colors) and reduced anticorrelations with dorsal attention network regions (cool colors). C and F) Contrast of young vs. older adults. In older adults, the MPFC shows reduced RSFC with other regions of the default network (cool colors), but increased RSFC with regions of the dorsal attention network (warm colors), relative to young adults. p < 0.05; FDR corrected.