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. 2016 Jun 29;4:2800410. doi: 10.1109/JTEHM.2016.2573305

FIGURE 10.

FIGURE 10.

Clinical interpretation flowchart. (a) A simple assay setup is depicted. Multiple reaction can be setup simultaneously allowing several antibiotics to be tested concurrently. A representative small footprint fluorimeter from Promega France (GloMax Discover) is shown as an example, though smaller handheld fluorimeters could also be used in principle. (b) Assay provides simple yes/no outputs as to whether Inline graphic-lactamase is produced and whether an antibiotic would be stable against cleavage. These outputs can be programmed into commercially available portable fluorimeters.