Table 3.
Methylation Levels of SFRP2, TFPI2, NDRG4, and BMP3
| Mean±SD | p-value | ||
|---|---|---|---|
|
| |||
| Tukey’s posttest | One-way ANOVA | ||
| SFRP2, % | |||
| NN | 29.9±16.5 | 0.039 | 0.013 |
| AN | 29.4±21.3 | 0.021 | |
| T | 49.8±26.1 | ||
| TFPI2, % | |||
| NN | 24.1±14.6 | 0.000 | 0.000 |
| AN | 23.6±18.4 | 0.000 | |
| T | 59.5±21.4 | ||
| NDRG4, % | |||
| NN | 33.8±21.8 | 0.024 | 0.003 |
| AN | 30.0±21.9 | 0.004 | |
| T | 51.8±27.5 | ||
| BMP3, % | |||
| NN | 16.9±13.6 | 0.003 | 0.001 |
| AN | 17.9±16.3 | 0.004 | |
| T | 35.7±10.8 | ||
SFRP2, secreted frizzled-related protein 2; TFPI2, tissue factor pathway inhibitor 2; NDRG4, N-Myc downstream-regulated gene 4; BMP3, bone morphogenic protein 3; ANOVA, analysis of variance; NN, non-adjacent normal appearing tissue; AN, adjacent normal appearing tissue; T, primary tumor tissue.