Table 1.
Baseline Characteristics
| HIV (n = 30) | Uninfected (n = 22) | P Value | ||
|---|---|---|---|---|
| Baseline demographics |
||||
| Age |
37.3 (9.2) | 47.9 (10.9) | 0.0004 | |
| Race, n (%) |
||||
| African American |
10 (33.3) | 14 (63.6) | 0.03 | |
| White |
20 (66.7) | 8 (36.4) | ||
| Sex, n (%) |
||||
| Female |
6 (20.0) | 5 (22.7) | 1.0 | |
| Male |
24 (80.0) | 17 (77.3) | ||
| Smoker, n (%) |
||||
| No |
9 (30.0) | 14 (63.6) | 0.016 | |
| Yes |
21 (70.0) | 8 (36.4) | ||
| Duration of HIV, yr |
||||
| Mean |
3.99 | N/A | ||
| Median |
1.75 | N/A | ||
| Obstructive lung disease, n |
||||
| COPD |
0 | N/A | ||
| Asthma |
2 | N/A | ||
| Pulmonary HTN, n |
0 | N/A | ||
| Prior PCP infection, n |
2 | N/A | ||
| Prior Kaposi sarcoma, n |
2 | N/A | ||
| | ||||
| BAL yields |
||||
| BAL fluid, ml |
123.1 ± 29.4 | 118.3 ± 33.0 | 0.589 | |
| Total cells, 106 |
59.5 ± 33.4 | 14.0 ± 16.3 | 0.006 | |
| Macrophages, % |
84.7 ± 12.3 | 88.2 ± 11.5 | 0.31 | |
| Lymphocytes, % |
13.5 ± 12.2 | 8.9 ± 9.8 | 0.16 | |
| Neutrophils, % |
1.5 ± 3.0 | 0.8 ± 1.0 | 0.25 | |
| Eosinophils, % | 0.3 ± 0.8 | 0.1 ± 0.3 | 0.31 | |
Definition of abbreviations: BAL = bronchoalveolar lavage; COPD = chronic obstructive pulmonary disease; HTN = hypertension; N/A = not applicable; PCP = Pneumocystis carinii pneumonia.