Table S2.

MWC allostery model fit parameters

PA	Peptide	pH	KdT, nM*	KdR, nM*	KdT/KdR*
WTPA	αl	5.6	3.1 (±0.3)	0.009 (±0.0004)	330 (±40)
	αd	5.6	3.8 (±0.4)	0.021 (±0.001)	180 (±20)

The stoichiometry, n, and equilibrium constant, K_TR, were fixed to 7 and 10¹⁵, respectively.

^*Data shown are mean (±SE).