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Time constants of the current decay were calculated at Ach concentrations that elicit 75% of Imax after fitting of the traces to one or two exponential decay function
| Type | LS [(α2)3(β2)2], τmean ± SEM (s) | HS [(α2)2(β2)3], τmean ± SEM (s) |
| α2β2 | τf = 2.63 ± 0.35*; τs = 40.17 ± 0.06 | τf = 8.48 ± 1.10*,†,‡ |
| α2W84Aβ2 | τf = 8.58 ± 2.35† | τf = 8.10 ± 1.16‡ |
P = 0.0023 this difference is statistical significant.
P > 0.5, this difference was not statistically significant.
