Table 5.
Multivariable Adjusted Odds Ratios for Positive Test Results by TST/QFT Category at Standard Cutoffs among the Foreign-Born U.S. Population 6 Years of Age and Older
| Adjusted OR (95 Confidence Interval)* |
|||
|---|---|---|---|
| TST+/QFT+ | TST+/QFT− | TST−/QFT+ | |
| Age, yr | |||
| 6–14 | Reference | Reference | Reference |
| 15–24 | 1.38 (0.16–11.9) | 1.46 (0.25–8.48) | 5.92 (0.45–77.4) |
| 25–44 | 3.01 (0.32–28.7) | 2.05 (0.44–9.65) | 7.01 (0.85–57.8) |
| 45–64 | 9.39 (0.82–108.2) | 3.07 (0.71–13.3) | 9.13 (1.49–56.0)† |
| ≥65 | 12.8 (1.07–153.8)† | 1.86 (0.40–8.55) | 16.1 (2.40–107.6)‡ |
| Male | 1.75 (1.00–3.08) | 0.92 (0.58–1.46) | 2.30 (1.28–4.12)‡ |
| Race/ethnicity | |||
| White | Reference | Reference | Reference |
| Black | 3.78 (0.91–15.6) | 2.72 (0.79–9.38) | 0.79 (0.16–3.90) |
| Asian | 7.38 (2.43–22.5)§ | 3.89 (0.96–15.8) | 1.52 (0.46–5.10) |
| Mexican-American | 5.45 (1.39–21.4)† | 2.01 (0.40–10.2) | 0.87 (0.19–4.02) |
| Other Hispanic | 4.21 (2.04–8.67)§ | 1.13 (0.32–3.95) | 0.67 (0.15–3.05) |
| Income at or below poverty line | 1.03 (0.63–1.67) | 1.38 (0.89–2.13) | 1.06 (0.43–2.63) |
| Diabetic | 1.76 (0.58–5.32) | — | 1.69 (0.87–3.26) |
| Current smoker | 1.25 (0.84–1.87) | 2.13 (0.94–4.81) | 0.67 (0.31–1.48) |
| Body mass index | |||
| Underweight | — | — | — |
| Normal | — | — | — |
| Overweight | — | — | — |
| Obese | — | — | — |
| TB exposure‖ | 1.19 (0.41–3.41) | 1.37 (0.56–3.38) | 3.00 (0.81–11.1) |
| Previous TST testing | 1.37 (0.76–2.46) | 1.36 (0.74–2.51) | 1.04 (0.47–2.29) |
| Past LTBI treatment | 4.38 (1.65–11.6)‡ | 2.03 (0.64–6.45) | 3.20 (1.13–9.05)† |
| Lymphocyte count¶ | — | 2.14 (1.41–3.26)‡ | — |
| Monocyte count¶ | 0.59 (0.39–0.88)† | 0.67 (0.41–1.10) | 1.47 (0.92–2.37) |
Definition of abbreviations: LTBI = latent tuberculosis infection; OR = odds ratio; QFT = QuantiFERON-TB Gold In-Tube test; TB = tuberculosis; TST = tuberculin skin test.
Data represent positive test results for TST 10 mm and QFT 0.35 IU/ml. Note that each column represents results from separate multivariable regression analyses. Boldface values are statistically significant at α = 0.05.
ORs are adjusted for all factors listed in the table (except for factors that had a P value >0.25 on univariate testing, which are denoted by dashes).
P < 0.05.
P ≤ 0.01.
P ≤ 0.001.
Includes personal or household contact history of active tuberculosis.
OR is per doubling of laboratory value.