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. 2016 Aug 29;11(8):e0161339. doi: 10.1371/journal.pone.0161339

Table 1. Characteristics of the 22 included studies in this meta-analysis.

Reference Nation Clinical type OLP(n/N) Control(n/N) Detection method HPV genotypes
Pol CA et al., 2015 India 21/30 0/30 IHC HPV16
Arirachakaran P et al., 2013 Thailand 1/37 0/37 PCR NA
Yildirim B et al., 2011 Turkey 14/65 0/15 IHC HPV16
Debanth S et al., 2009 India 6/6 3/35 PCR HPV16, 18, 31, 33, 35, 39, 45, 51,52, 56, 58, 59,68
Fehér E et al., 2009 Hungary 39/119 3/72 PCR HPV6.11.16.18.31.33
Razavi SM et al., 2009 Iran 9/29 1/14 PCR HPV18
Szarka K et al., 2009 Hungary 39/119 3/72 PCR NA
EA-OLP 26/61 3/72
non-EA-OLP 13/58 3/72
Yu Hong et al., 2007 China 33/57 3/20 PCR HPV16
Cianfriglia F et al., 2006 Italy 3/15 2/10 ISH NA
Giovannelli L et al., 2006 Italy 12/49 11/49 PCR NA
Campisi G et al., 2004 Italy 14/71 5/90 PCR HPV16.18.31.6
EA-OLP 9/44 5/90
non-EA-OLP 5/27 5/90
Ma Jian et al., 2003 China 26/30 5/18 PCR NA
OFlatharta C et al., 2003 Ireland 10/38 0/20 PCR HPV16
Giovannelli L et al., 2002 Italy 9/34 5/90 PCR NA
Li Hui et al., 2000 China 9/30 3/40 PCR NA
Sand L et al., 2000 Sweden 6/22 0/12 NA NA
Qi Yanchun et al., 1999 China 9/30 3/40 PCR NA
Lei Lei et al., 1997 China 9/22 2/10 PCR NA
EA-OLP 3/4 2/10
non-EA-OLP 6/18 2/10
Vespe M et al., 1997 Germany 3/7 0/33 PCR HPV16.18.31
Boyd AS et al., 1996 USA 11/13 0/10 PCR NA
Cox M et al., 1993 UK 3/4 3/5 PCR HPV16
Maitland NJ et al., 1987 UK 7/8 5/12 PCR HPV16

n: numbers of HPV positive subjects; N: numbers of total subjects; IHC: immunohistochemical staining; PCR: polymerase chain reaction; ISH: in situ hybridization; NA: not available; EA-OLP: erosive-atrophic oral lichen planus; non-EA-OLP: non-erosive-atrophic oral lichen planus.