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. 2016 Aug 29;11(8):e0161903. doi: 10.1371/journal.pone.0161903

Table 1. Patient characteristics.

All women Pre-menopausal Post-menopausal
n = 162 n = 81 n = 81
Number (%)
Age (mean ± SD, years) 52.6 ± 7.9 46.8 ± 5.8 58.3 ± 4.9
BMI (mean ± SD, kg/m2) 27.0 ± 5.6 26.3 ± 5.6 27.7 ± 5.5
    <25 67 (41.4) 39 (48.2) 28 (34.6)
    25-<30 59 (36.4) 29 (35.8) 30 (37.0)
    ≥30 36 (22.2) 13 (16.1) 23 (28.4)
Smoking status
    Never 69 (42.6) 41 (50.6) 28 (34.6)
    Former 72 (44.4) 29 (35.8) 43 (53.1)
    Current 21 (13.0) 11 (13.6) 10 (12.4)
Alcohol consumption (mean ± SD, drink per week) 4.3 ± 4.6 4.5 ± 4.2 4.1 ± 5.0
Physical activity (mean ± SD, MET-hours per week)
    Total 118.6 ± 51.4 137.5 ± 47.2 99.7 ± 48.6
    Occupational 63.6 ± 45.6 79.9 ± 37.6 47.4 ± 47.3
    Transportation-related 0.7 ± 2.0 0.8 ± 2.3 0.7 ± 1.7
    Household 36.0 ± 23.3 36.2 ± 24.0 35.7 ± 22.6
    Recreational 18.3 ± 17.0 20.6 ± 19.1 16.0 ± 14.3
Stage
    0 16 (9.9) 9 (11.1) 7 (8.6)
    I 64 (39.5) 33 (40.7) 31 (38.3)
    II 66 (40.7) 35 (43.2) 31 (38.3)
    III 16 (9.9) 4 (5.0) 12 (14.8)
Histological type
    Ductal, in-situ 16 (9.9) 9 (11.1) 7 (8.6)
    Ductal, invasive 121 (74.7) 66 (81.5) 55 (67.9)
    Lobular, invasive 15 (9.3) 4 (4.9) 11 (13.6)
    Others* 10 (6.1) 2 (2.5) 8 (9.9)
Tumor grade
    Non-assessable 26 (16.0) 11 (13.6) 15 (18.5)
    1 29 (17.9) 15 (18.5) 14 (17.3)
    2 68 (42.0) 36 (44.4) 32 (39.5)
    3 39 (24.1) 19 (23.5) 20 (24.7)
ER status
    Positive 145 (89.5) 74 (91.4) 71 (87.6)
    Negative 17 (10.5) 7 (8.6) 10 (12.4)
PR status
    Positive 136 (84.0) 74 (91.4) 62 (76.5)
    Negative 26 (16.0) 7 (8.6) 19 (23.5)
HER2 status
    Not evaluated 28 (17.3) 11 (13.6) 17 (21.0)
    Positive 18 (11.1) 8 (9.9) 10 (12.3)
    Negative 116 (71.6) 62 (76.5) 54 (66.7)

SD: Standard deviation; BMI: Body mass index; MET-hours: metabolic equivalent hours of activity; ER: Estrogen receptor; PR: Progesterone receptor; HER2: Human epidermal growth factor receptor 2

*: includes mucinous, tubular, adenoid cystic and metaplastic carcinomas