Fig 2. Normalized Saa3 mRNA levels in lung tissue from ApoE-/- mice after repeated i.t. instillations of carbon black (CB) and/or lipopolysaccharide (LPS).
Fold increase in mRNA levels of Saa3 compared to the vehicle group are shown. Open circles and squares represent the individual mice. Minus (-) denotes no exposure, plus denotes low (+) or high-dose (++) exposure. Lines represent the mean in each group (N = 9–10 per group). Asterisk denotes ***P<0.001 compared to the LPS exposed group, and #P<0.05, ##P<0.01, ###P<0.001 compared to the vehicle control, two-factor ANOVA with Fisher’s LSD post-hoc test.