Table 3.

Meta-Analysis of SNPs With BP Traits

		Millennium GPJ			Global BPgen			Pooled
SNP	Coded Allele	n (Frequency)	Coefficient (SE), mm Hg	P	n (Frequency)	Coefficient (SE), mm Hg	P	Coefficient (95% CI), mm Hg	P
Systolic BP
FGF5	T	13 826	1.33	1.6×10−8	30 850	0.62	1.6×10−6	0.81	1.1×10−11
rs1458038		(0.343)	(0.23)		(0.275)	(0.14)		(0.58 to 1.05)
CYP17A1	A	14 007	0.89	2.3×10−4	33 735	0.94	1.0×10−5	0.92	6.2×10−9
rs1004467		(0.680)	(0.24)		(0.901)	(0.21)		(0.61 to 1.23)
CSK	C	13 920	0.77	0.007	34 126	0.62	2.4×10−6	0.65	4.2×10−8
rs1378942		(0.803)	(0.28)		(0.36)	(0.13)		(0.42 to 0.88)
PLCD3	T	14 003	0.11	0.703	32 120	0.68	3.9×10−6	0.57	2.5×10−5
rs12946454		(0.831)	(0.30)		(0.28)	(0.15)		(0.30 to 0.83)
PLEKHA7	T	14 030	0.11	0.687	33 706	0.52	2.6×10−4	0.44	4.7×10−4
rs381815		(0.199)	(0.28)		(0.26)	(0.14)		(0.19 to 0.68)
CSK-ULK3	A	14 014	0.68	0.017	33 308	0.47	2.4×10−4	0.51	1.7×10−5
rs6495122		(0.812)	(0.28)		(0.45)	(0.13)		(0.28 to 0.74)
ULK4	A	13 976	−0.67	0.059	32 034	0.17	0.297	0.01	0.950
rs9815354		(0.116)	(0.35)		(0.18)	(0.17)		(−0.29 to 0.31)
DBP
FGF5	T	13 826	0.73	1.8×10−7	30 850	0.55	1.5×10−8	0.61	6.1×10−14
rs1458038		(0.343)	(0.14)		(0.275)	(0.10)		(0.45 to 0.77)
CYP17A1	A	14 007	0.29	0.047	33 735	0.40	5.4×10−3	0.35	4.9×10−4
rs1004467		(0.680)	(0.14)		(0.901)	(0.14)		(0.15 to 0.54)
CSK	C	13 920	0.41	0.015	34 126	0.48	5.9×10−8	0.46	5.2×10−9
rs1378942		(0.803)	(0.17)		(0.36)	(0.09)		(0.31 to 0.62)
PLCD3	T	14 003	0.14	0.426	32 120	0.34	5.7×10−4	0.30	1.9×10−4
rs12946454		(0.831)	(0.18)		(0.28)	(0.09)		(0.14 to 0.46)
PLEKHA7	T	14 030	0.13	0.437	33 706	0.23	0.014	0.20	0.018
rs381815		(0.199)	(0.17)		(0.26)	(0.10)		(0.04 to 0.37)
CSK-ULK3	A	14 014	0.38	0.027	33 308	0.35	4.2×10−5	0.36	7.4×10−6
rs6495122		(0.812)	(0.17)		(0.45)	(0.09)		(0.20 to 0.51)
ULK4	A	13 976	0.21	0.325	32 034	0.40	2.9×10−4	0.36	2.3×10−4
rs9815354		(0.116)	(0.21)		(0.18)	(0.11)		(0.17 to 0.55)